Mounjaro and Alcohol: Can I Have a Drink if I Take This Medication?

December 19, 2023

Medications like Mounjaro, Ozempic, and Wegovy are hot topics everywhere, from social media to the international press.

These glucagon-like peptide-1 (GLP-1) agonists effectively treat type 2 diabetes, but they’re also earning unprecedented attention for the superior weight loss results they deliver to many patients with obesity.

As a direct primary care physician, I’m excited to see my patients successfully losing excess weight — and feeling happier and healthier — thanks to GLP-1 medications.

Some patients have questions concerning Mounjaro (tirzepatide) and certain lifestyle choices, such as drinking alcohol. Two of the most common are:

  • If I’m taking Mounjaro, is it safe to drink alcoholic beverages?
  • If so, how much alcohol is okay?

When taken to promote weight loss, there is no known dangerous interaction between Mounjaro and alcohol. However, medication manufacturers recommend that people taking GLP-1 agonists either limit alcohol consumption or abstain from alcohol entirely.

INFOGRAPHIC: Mounjaro and Alcohol: Can I Have a Drink if I Take This Medication?

Effects of Alcohol and Mounjaro

Alcoholic beverages are loaded with empty calories, and consuming them can counteract a GLP-1 agonist’s impact on weight loss. Alcohol can also lower a person’s inhibitions. Your ability to resist eating unhealthy foods may disappear once you’ve consumed a drink or two, further disrupting your weight loss efforts.

Additionally, when Mounjaro and alcohol collide, stomach distress can ensue. GLP-1 medications slow activity within the gastrointestinal (GI) tract. In other words, your stomach moves food forward at a slower pace.

A slowed digestive process means you must carefully manage what you eat and drink, as well as how much and how often.

Two margaritas, for instance, carry a lot of high-calorie fluid for a Mounjaro user to put in their stomach. On top of that, when the alcohol weakens your inhibitions and your hunger returns, you may order those nachos you spotted on the menu.

After consuming margaritas and nachos, your stomach may become bloated and uncomfortable. Because the combination of Mounjaro and alcohol slows your digestion, it’ll feel that way for a while.

Your food may feel like it’s coming back up, causing heartburn or the urge to vomit. You may even experience constipation due to your slower GI.

So, that pair of seemingly innocent adult beverages could cause you physical discomfort, hamper your medication’s effectiveness, and sabotage your weight loss goals.

QUOTE: Mounjaro and Alcohol: Can I Have a Drink if I Take This Medication?

Mounjaro and Alcohol: Less Is Better

To avoid counteracting Mounjaro’s effects and to steer clear of stomach discomfort, listen to the GLP-1 drug manufacturers and limit how much you drink — or, better yet, abstain from alcohol altogether.

If you choose to invest your time, health, and money into Mounjaro, you want to maximize your results. It’s a good idea to consume as little alcohol as possible.

Your Priority Physicians are always happy to provide answers and advice about your medications and to counsel you on potential interactions or side effects. And if you’re having great success with weight loss medication, reach out and share your story. We’d love to celebrate with you!

Dr. Jonathan Schmidt

Dr. Schmidt is a board-certified family medicine physician with undergraduate degrees in Microbiology and medicine from Southern Illinois University and the University of Illinois. He completed his residency at St. Joseph Regional Medical Center in South Bend, IN and has a passion for putting his patients first in his practice. In his free time, Dr. Schmidt enjoys spending time with his family and participating in outdoor activities such as water sports and woodworking.

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